Researchers at ETH Zürich recently published a proof of concept paper regarding oral drug delivery using 3D printed mouthguards.
According to the paper, “A primary reason for the gap between prototyping and application is that, although ample progress has been made in 3D printing technologies, the materials and standardized procedures remain generally inadequate from a pharmaceutical perspective, hampering the development of consistent, scalable, 3D-printed drug-eluting devices.”
(A) 3D printed VA-loaded mouthguards with three different designs: HSPH, VSPH, and HSPL
(B) Representative images of the 3D printed VA-loaded mouthguards tailored to each volunteer’s maxillary anatomy in the HSPH group.